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KMID : 0387820110180010034
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Clinical Pediatric Hematology-Oncology
2011 Volume.18 No. 1 p.34 ~ p.39
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Clinical Features and Treatment Outcomes of Hemangioma in a Single Institution
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Chung Sun-Hee
Park Dong-Hyuk
Shim Jae-Won
Kim Duk-Soo
Shim Jung-Yeon
Park Moon-Soo
Jung Hye-Lim
Koo Hong-Hoe
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Abstract
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Background: Hemangiomas are the most common benign tumor of childhood. Uncertainties regarding their diagnosis or management often prompt life- or function-threatening complications or unnecessary treatment. The objective of this study is to analyze and understand the clinical features and treatment outcomes of hemangiomas for accurate diagnosis and treatment.
Methods: A retrospective chart review of 60 patients diagnosed as hemangioma in Kangbuk Samsung Hospital from January 2001 to January 2011 was performed.
Results:Hemangiomas were observed predominantly in female with the sex ratio of 1:2.2. They were present at birth in 32%, and within 2 months of age in 22% of the patients. In 45% of the patients, hemangiomas occurred on the head and neck, which were the most commonly involved site. 27% of the cases were clinically diagnosed, 40% of the cases were diagnosed after imaging studies, and 37% of cases were confirmed by histopathology. 40% of the patients were observed without treatment. 57% of the patients were treated with surgical excision, corticosteroid, interferon or propranolol. Eight patients were treated with oral propranolol, and seven of them demonstrated regression without major side effects.
Conclusion: We confirmed that hemangiomas were preponderant in female and usually appeared in first 2 months of life, and the head and neck were the most favored site. We observed that propranolol was effective and safe for treating problematic infantile hemangiomas.
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KEYWORD
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Hemangioma, Propranolol
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